Max Planck Institute for Molecular Genetics, Berlin, Germany

www.molgen.mpg.de

The Max Planck Institute for Molecular Genetics (MPIMG) is one of the key research institutes for molecular biology research and is perceived internationally as a stronghold of genome and genetics research. The overall research goal is to gain new insights into the development of diseases on a molecular level, thus contributing to the development of novel cause-related medical treatments. The MPIMG is one of the largest next generation sequencing centers in Europe and has outstanding expertise in the field of NGS technology development.

Dr. Babette Regierer

studied biology at the Free University Berlin and did her PhD on plant nutrition at the Max Planck Institute for Molecular Plant Physiology (www.mpimp-golm.mpg.de). After her postdoc position in the frame of a European research consortium on phosphate efficiency in higher plants she specialized in scientific project coordination and management in the area of functional genomics and technology development. She broadened her skills working as a project manager for an agency in technology transfer and patent commercialization (www.iapl.de) and established the Potsdam Research Network pearls (www.pearlsofscience.de). Dr. Babette Regierer is currently working at the Max Planck Institute for Molecular Genetics and involved in the European initiative “IT Future of Medicine” to develop a ‘virtual patient’ model (www.itfom.eu), but is also participating in the COST Action SeqAhead, a network for NGS data analysis (www.seqahead.eu).

Publications

Hoehenwarter W, van Dongen JT, Wienkoop S, Steinfath M, Hummel J, Erban A, Sulpice R, Regierer B, Kopka J, Geigenberger P, Weckwerth W (2008) A rapid approach for phenotype-screening and database independent detection of cSNP/protein polymorphism using mass accuracy precursor alignment. Proteomics 8 (20): 4214-4225.

Geigenberger P, Regierer B, Nunes-Nesi A, Leisse A, Urbanczyk-Wochniak E, Springer F, van Dongen JT, Kossmann J, Fernie AR (2005) Inhibition of de novo pyrimidine synthesis in growing potato tubers leads to a compensatory stimulation of the pyrimidine salvage pathway and a subsequent increase in biosynthetic performance. Plant Cell. 17(7):2077-88. Epub 2005 Jun 10.

Zimmermann P, Regierer B, Kossmann J, Frossard E, Amrhein N, Bucher M (2004) Differential expression of three purple acid phosphatases from potato. Plant Biol (Stuttg) 6(5), 519-28

Geigenberger P, Regierer B, Lytovchenko A, Leisse A, Schauer N, Springer F, Kossmann J, Fernie AR (2004) Heterologous expression of a ketohexokinase in potato plants leads to inhibited rates of photosynthesis, severe growth retardation and abnormal leaf development. Planta 218(4), 569-78

Regierer B, Fernie AR, Springer F, Perez-Melis A, Leisse A, Koehl K, Willmitzer L, Geigenberger P, Kossmann J (2002) Starch content and yield increase as a result of altering adenylate pools in transgenic plants. Nat Biotechnol Dec, 20(12):1256-60

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